US regulators have approved Roche’s Zelboraf (vemurafenib) for patients with a rare blood condition called Erdheim-Chester disease (ECD) carrying a mutation called BRAF V600
Roche is planning to initiate late-stage studies investigating potential combinations for patients with advanced skin cancer based on its immunotherapy Tecentriq, which is already on the market for lung and bladder cancer.
Patients in England and Wales with a certain type of advanced skin cancer will not be getting routine access to Roche’s Cotellic/Zelboraf combination on the NHS, after it was turned down by the National Institute for Health and Care Excellence.