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More than nine out of every 10 lung cells in current smokers have up to 10,000 extra genetic changes compared to non-smokers.

If approved, it will become the first therapy to specifically target METex14 mutated advanced lung cancer, a type of lung cancer with a particularly poor prognosis.

Despite evidence suggesting that the Keytruda combo would be welcomed by patients, NICE cites uncertainty around the long-term benefit.

The company will also make the UK the global centre of a major new clinical trial to investigate the use of inclisiran in improving cardiovascular outcomes.

Despite the recent approval of some high-profile nucleic acid therapy drugs, success has been modest, and there is still a “huge burden” of unmet medical need due to the vast number of diseases that are untreatable with traditional therapies.

The EMA also recently validated a Marketing Authorisation Application for the drug.

The number of patients with multiple long-term conditions is going up as the population ages, putting pressure on primary and secondary care.

Almost 1,800 new nursing apprentices have already started their training over the last couple of years.

The process is intended for for extremely rare conditions.

A research team forced cancer cells in the lab to evolve much more rapidly than usual using a molecule called APOBEC3B, which could then be used to create a vaccine for each individual cancer type.

China’s National Health Commission has confirmed a virus death toll rise to 908, surpassing the toll from the SARS epidemic of 2002-3, according to official data.

Alzheimer’s is a complex disease and one of the largest challenges facing healthcare today, with lots of failed treatments in past pipelines.

Experts are calling for the hormone to be offered as standard in the NHS for women with early pregnancy bleeding and a history of miscarriage.

The two separate ventures are part of a drive to expand the latest technological innovations and digital solutions in ophthalmology.