Over the past two decades, clinical trials have undergone significant transformation.
Historically, trials followed a paternalistic and analogue model with sponsors and investigators dictating the process to participating patients, often with little consideration for how they felt or how they wanted to engage with the activities they were asked to complete.
Trial activities took place on-site and relied primarily on physiological endpoints – imaging, biomarkers, lab tests – while disregarding the lived experience of the patient.
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